Tailoring host cell specific delivery and bioavailability of antimycobacterial compounds using peptide decorated nanocarriers

Description of the research topic:

To summarize the major reasons for the need of novel antimycobacterial agents, the followings should be considered: (i) the increasing emergence of MDR, NTM and fast growing strains and (ii) dormant bacilli in host cells (iii) the new compounds should have a novel mechanism of action (iv) to enhance the cellular uptake and bioavailability with host cell specific carrier systems. Identification of new chemotherapeutics has crucial benefits. To enhance the cellular uptake of the active compounds, different approaches will be developed. Due to the optimised cellular uptake, more effective therapy can be achieved.

Thesis supervisor: Szilvia Bősze

Required language skills: English
Recommended language skills (in Hungarian): Hungarian
Further requirements: Biology MSc, Chemistry MSc, Microsoft Office, Origin, Prism, basic cell culturing

How to Apply?

If you are interested apply here: [PhD] Hevesy György PhD School of Chemistry – Eötvös Loránd University (elte.hu)

For more information visite the following website: Doctoral School of Chemistry (elte.hu)

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